Combretastatin D-2

SANC00710

Entry name:

Combretastatin D-2

Formula:

C₁₈H₁₆O₄

Molecular mass:

296.32

ChemSpider ID:

9954004

CAS No.

126191-23-9

2D Image 3D View

SMILES:

O=C2CCc1ccc(O)c(c1)Oc3ccc(C=CCO2)cc3

Scaffold SMILES:

c1ccccc1
O=C1CCc2cccc(c2)Oc2ccc(cc2)C=CCO1

References

Singh & Singh (1990) Antineoplastic agents. 206. Structure of the cytostatic macrocyclic lactone combretastatin D-2

Classifications

Macrocyclic lactone

Macrolides and analogues (Classyfire)

Other Names

2,11-Dioxatricyclo[13.2.2.13,7]Eicosa-3,5,7(20),13,15,17,18-Heptaen-10-One, 4-Hydroxy-, (Z)-

Source Organisms

Combretum caffrum

Compound Uses

P-388 lymphocytic leukemia (PS) cell line growth inhibition

Cytostatic