SANC00709



Combretastatin D-1





C18H16O5









117709-78-1



SMILES:

O=C4CCc1ccc(O)c(c1)Oc2ccc(cc2)C3OC3CO4





References

  • Pettit et al. (1988) Antineoplastic agents. 160. Isolation and structure of combretastatin D-1: a cell growth inhibitory macrocyclic lactone from Combretum caffrum

  • Classifications

  • Macrocyclic lactone

  • Other Names

  • 3,6,15-Trioxatetracyclo[14.2.2.110,14.02,4]Heneicosa-10,12,14(21),16,18,19-Hexaen-7-One, 13-Hydroxy-, [2S-(2R*,4S*)]-
  • (-)-Combretastatin D1

  • Source Organisms

  • Combretum caffrum

    Compound Uses

  • P-388 lymphocytic leukemia (PS) cell line growth inhibition
  • Cytostatic activity