SANC00674



Combretastatin A-3





C17H18O5









111394-45-7



SMILES:

COc2ccc(/C=C\c1cc(O)c(OC)c(OC)c1)cc2O





References

  • Pettit & Singh (1987) Isolation, structure, and synthesis of combretastatin A-2, A-3, and B-2

  • Classifications

    Unclassified

    Other Names

  • Combretastatin A-3
  • Phenol, 5-[(1Z)-2-(3-Hydroxy-4-Methoxyphenyl)Ethenyl]-2,3-Dimethoxy-
  • Phenol, 5-[2-(3-Hydroxy-4-Methoxyphenyl)Ethenyl]-2,3-Dimethoxy-, (Z)-
  • Combretastatin 3
  • Combretastatin A3

  • Source Organisms

  • Combretum caffrum

    Compound Uses

  • Murine P388 lymphocytic leukemia (PS) cell-growth inhibition
  • Tubulin inhibitory activity