SANC00618



3β,16β,17α-Trihydroxycholest-5-en-22-one 3-O-β-D-glucopyranoside 16-O-{O-(2-E-cinnamoyl-β-D-xyopyranosyl)-(1→3)-2-O-acetyl-α-L-arabinopyranoside}





C54H78O19









183729-13-7



SMILES:

[H][C@@]8(O[C@H]5C[C@@]4([H])[C@]3([H])CC=C2C[C@@H](O[C@]1([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)CC[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@]5(O)[C@H](C)C(=O)CCC(C)C)OC[C@H](O)[C@H](O[C@]6([H])OC[C@@H](O)[C@H](O)[C@H]6OC(=O)/C=C/c7ccccc7)[C@H]8OC(C)=O





References

  • Mimaki et al. (1997) Cholestane glycosides with potent cytostatic activities on various tumor cells from Ornithogalum saundersiae bulbs

  • Kuroda et al. (2001) Cholestane Glycosides from the Bulbs of Galtonia candicans and Their Cytotoxicity

  • Classifications

  • Cholestane

  • Glycoside

  • Other Names

  • Cholest-5-En-22-One, 16-[[2-O-Acetyl-3-O-[2-O-[(2E)-1-Oxo-3-Phenyl-2-Propenyl]-[Beta]-D-Xylopyranosyl]-[Alpha]-L-Arabinopyranosyl]Oxy]-3-([Beta]-D-Glucopyranosyloxy)-17-Hydroxy-, (3[Beta],16[Beta])- (9Ci)
  • Cholest-5-En-22-One, 16-[[2-O-Acetyl-3-O-[2-O-[(2E)-1-Oxo-3-Phenyl-2-Propen-1-Yl]-[Beta]-D-Xylopyranosyl]-[Alpha]-L-Arabinopyranosyl]Oxy]-3-([Beta]-D-Glucopyranosyloxy)-17-Hydroxy-, (3[Beta],16[Beta])-
  • 3[Beta],16[Beta],17[Alpha]-Trihydroxycholest-5-En-22-One 3-O-[Beta]-D-Glucopyranoside 16-O-{O-(2-E-Cinnamoyl-[Beta]-D-Xyopyranosyl)-(1[To]3)-2-O-Acetyl-[Alpha]-L-Arabinopyranoside}
  • 16[Beta]-[(O-(2-O-(E)-Cinnamoyl-[Beta]-D-Xylopyranosyl)-(1[To]2)-2-O-Acetyl-[Alpha]-L-Arabinopyranosyl)Oxy]-3[Beta]-[([Beta]-D-Glucopyranosyl)Oxy]-17[Alpha]-Hydroxycholest-5-En-22-One

  • Source Organisms

  • Ornithogalum saundersiae
  • Galtonia candicans

    Compound Uses

  • Cytostatic activity against HL-60 leukemia cells
  • Cytotoxic activity on HL-60 leukemia cells