SANC00213



Spongiostatin 5





C59H89ClO19













153698-80-7



SMILES:

[H][C@]23C=CCCC[C@@]1([H])O[C@](O)(C[C@H](O)[C@H]1C)[C@@H](O)[C@@H]8O[C@H](CC(=C)C[C@H](O)/C=C/C(=C)Cl)[C@@H](O)[C@H](OC(=O)C[C@@]7([H])C[C@H](O)C[C@@]6(C[C@@](C)(O)C[C@]([H])(C=C5CO[C@H]([C@H](C)C(=O)C[C@]4([H])C[C@H](OC)C[C@](C[C@@H](O)C2)(O3)O4)C5C)O6)O7)C8C





References

  • Pettit et al. (1993) Isolation and structure of the powerful human cancer cell growth inhibitors spongistatins 4 and 5 from an African Spirastrella spinispirulifera (Porifera)

  • Classifications

  • Polyketide

  • Other Names

  • Spongistatin 5
  • 9,35,39,46,48,49,50,52-Octaoxaoctacyclo[40.3.1.11,5.17,10.114,18.118,22.128,32.134,38]Dopentaconta-6,23-Diene-12,40-Dione, 36-[(4S,5E)-7-Chloro-4-Hydroxy-2-Methylene-5,7-Octadienyl]-3,20,30,32,33,37,44-Heptahydroxy-16-Methoxy-3,11,29,47,51-Pentamethyl-, (
  • 9,35,39,46,48,49,50,52-Octaoxaoctacyclo[40.3.1.11,5.17,10.114,18.118,22.128,32.134,38]Dopentaconta-6,23-Diene-12,40-Dione, 36-(7-Chloro-4-Hydroxy-2-Methylene-5,7-Octadienyl)-3,20,30,32,33,37,44-Heptahydroxy-16-Methoxy-3,11,29,47,51-Pentamethyl-, [1R-[1R*,

  • Source Organisms

  • Spirastrella spinispirulifera (Porifera)

    Compound Uses

  • Anticancer activity